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23 Kim et al. A randomized controlled trial of a probiotic, VSL#3, on gut transitand symptoms in diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2003; 17:895-904

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25 Wong et al. Melatonin Regulation as a Possible Mechanism for Probiotic (VSL#3) in Irritable Bowel Syndrome: A Randomized Double-Blinded Placebo Study. Dig Dis Sci. 2014

26 Bibiloni et al. VSL#3* Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis. Am J Gastroenterology 2005;100:1539-1546

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In addition to the above-referenced studies ExeGi takes the position that studies performed on VSL#3®️* as produced before January 31, 2016, are also relevant to the evaluation the efficacy and safety of Visbiome.

*VSL#3®️ is a registered trademark of, and is manufactured exclusively for, VSL Pharmaceuticals, Inc. Visbiome is manufactured exclusively for ExeGi Pharma, LLC and is not affiliated with, endorsed by, or distributed by VSL Pharmaceuticals, Inc. 

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