What Is Visbiome®?

More than 25 years ago, Professor Claudio De Simone developed his lauded De Simone Formulation probiotic at his lab in Rome.

Today, the De Simone Formulation can be found only in Visbiome, a high potency probiotic medical food containing 8 strains of live bacteria in concentrations of 450 billion per packet and 112.5 billion per capsule – one of the highest concentrations available.

visbiome high potency probiotic

What Is Visbiome®?

More than 25 years ago, Professor Claudio De Simone developed his lauded De Simone Formulation probiotic at his lab in Rome.

Today, the De Simone Formulation can be found only in Visbiome, a high potency probiotic medical food containing 8 strains of live bacteria in concentrations of 450 billion per packet and 112.5 billion per capsule – one of the highest concentrations available.

visbiome high potency probiotic

What Is Visbiome®?

More than 25 years ago, Professor Claudio De Simone developed his lauded De Simone Formulation probiotic at his lab in Rome.

Today, the De Simone Formulation can be found only in Visbiome, a high potency probiotic medical food containing 8 strains of live bacteria in concentrations of 450 billion per packet and 112.5 billion per capsule – one of the highest concentrations available.

What Is Visbiome®?

More than 25 years ago, Professor Claudio De Simone developed his lauded De Simone Formulation probiotic at his lab in Rome.

Today, the De Simone Formulation can be found only in Visbiome, a high potency probiotic medical food containing 8 strains of live bacteria in concentrations of 450 billion per packet and 112.5 billion per capsule – one of the highest concentrations available.

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With more than 100 published human clinical studies, Visbiome products are the most studied multi-strain probiotics on the market today and have been proven as an effective aid in the management of dysbiosis, or microbial imbalance, associated with:  

Irritable Bowel Syndrome (IBS)

Ulcerative Colitis (UC)

Antibiotic-Associated Diarrhea (AAD)

Hepatic Encephalopathy (HE) 

Ileal Pouch Management

What is dysbiosis?  

In the context of the gut microbiome, dysbiosis typically refers to an imbalance in the ratio of beneficial to harmful bacteria, which can lead to a variety of health problems, including gastrointestinal disorders, autoimmune disorders, and metabolic diseases. Overall, dysbiosis is a complex and multifactorial condition that can have significant impacts on human health and well-being.

What Makes Visbiome Effective?  

Visbiome contains highly concentrated natural yogurt bacteria which are grown using dairy ingredients to ensure their health and vitality. (Trace levels of dairy may be present in the final product).

Our proprietary cocktail contains the following bacterial strains selected due to their individual characteristics and synergistic activities. They are cultured from proprietary Master Cell Banks and manufactured using specific ratios.

  • L. acidophilus DSM24735
  • L. plantarum DSM24730
  • L. paracasei DSM24733
  • L. delbrueckii subsp. bulgaricus DSM24734
  • S. thermophilus DSM24731
  • B. longum** DSM24736
  • B. breve DSM24732
  • B. infantis** DSM24737
  • L. acidophilus DSM24735
  • L. plantarum DSM24730
  • L. paracasei DSM24733
  • L. delbrueckii subsp. bulgaricus DSM24734
  • S. thermophilus DSM24731
  • B. longum** DSM24736
  • B. breve DSM24732
  • B. infantis** DSM24737

Visbiome's Formula Bacteria Strains

Genus

Species

Strain References

Lactobacillus paracasei DSM 24733/SD5218
Lactobacillus plantarum DSM 24730/SD5209
Lactobacillus acidophilus DSM 24735/SD5212
Lactobacillus delbrueckii subspecies bulgaricus* DSM 24734/SD5210
Bifidobacterium longum± DSM 24736/SD5219
Bifidobacterium infantis± DSM 24737/SD5220
Bifidobacterium breve DSM 24732/SD5206
Streptococcus thermophilus DSM 24731/SD5207

±Reclassified as Bifidobacterium lactis
*Reclassified as Lactobacillus helveticus 

  • L. acidophilus DSM24735
  • L. plantarum DSM24730
  • L. paracasei DSM24733
  • L. delbrueckii subsp. bulgaricus DSM24734
  • S. thermophilus DSM24731
  • B. longum** DSM24736
  • B. breve DSM24732
  • B. infantis** DSM24737

Dairy Status

Visbiome contains trace amounts of milk
Some of the strains of beneficial probiotic bacteria found in in Visbiome® are grown in a dairy environment and then blended with the rest of the strains to obtain the Visbiome Formulation. The bacteria are separated from the growth media however some trace levels of milk can be found in the finished product. Visbiome® contains traces of milk in the finished product.

Visbiome is Lactose-Free
Processing methods eliminate lactose even though other milk components are left behind (similar to lactose-free milk). Lactose was not detectable in amounts greater than 50 parts per million (PPM). 

If you have sensitivity to dairy, please consult with your healthcare professional prior to taking Visbiome® or Visbiome® Extra Strength.

Monash University, the leader in FODMAP research has also officially certified Visbiome as Low FODMAP. FODMAPs are sugars that aren’t absorbed properly in the gut, triggering symptoms in people with IBS and other gut related conditions. Follow this link to learn more about the LOW FODMAP diet.

Dosing Information

Visbiome is intended for use under the supervision of a physician.

Visbiome Extra Strength is a prescription only medical food intended for high-dose applications (900 billion bacteria per packet) under elevated medical supervision.  

Visbiome  Formulations - All Oral Administration

Product Bacteria Count (in CFUs) Content NHRIC Code

Visbiome GI Care

112.5B per capsule

60 capsules per bottle

69355-0412-03

Visbiome Advance GI Care

450B per packet

30 packets per box

69355-0412-02

Visbiome Extra Strength
(Dispensed by Prescription)

900B per packet

30 packets per box

69355-0516-01

Adult Visbiome Recommended Daily Intake by Medical Food Applications

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Visbiome GI Care Visbiome Advance GI Care Visbiome Extra Strength Packets

Irritable Bowel Syndrome (IBS)
1 - 4 Capsule(s)
112.5 - 450B CFU

Advanced Irritable Bowel Syndrome
1 Packet
450B CFU

Advanced Ulcerative Colitis
1 Packet
900B CFU

Under Antibiotic Treatment
4 Capsules
450B CFU

After Antibiotic Treatment
2 Capsules (for at least 10 days)
225B CFU

Ulcerative Colitis
1-2 Packet(s)
450-900B CFU

Ileal Pouch Management
1-2 Packet(s)
900-1800B CFU

Hepatic Encephalopathy
2-4 Capsules
225-450B CFU

Adult Visbiome Recommended Daily Intake by Medical Food Applications

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Age Irritable Bowel Syndrome (IBS) Advanced Irritable Bowel Syndrome (IBS) Ulcerative Colitis (UC)
2 – 5 Years 1 Capsule
112.5B CFU
2 Capsules
225B CFU
1/2 Advance GI Care Packet
225B CFU
6 – 11 Years 1-2 Capsule(s)
112.5 - 225B CFU
1 Advance GI Care Packet
450B CFU
1 Advance GI Care Packet
450B CFU
12 – 17 Years 1-4 Capsule(s)
112.5 - 450B CFU
1 Advance GI Care Packet
450B CFU
1 - 2 Advance GI Care Packet(s)
450 - 900B CFU
   

Peace of Mind with Visbiome® Temperature Monitor

Visbiome is shipped and stored under refrigerated conditions (36-46°, 2-8°C) to ensure vitality. Every order is shipped with a temperature monitoring sensor specifically calibrated for Visbiome. This card helps to ensure your order was not compromised by heat events during transit.

Visbiome can be stored at room temperature for up to one week without adversely affecting potency.

Temperature Monitor
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Peace of Mind with Temperature Monitor

Visbiome is shipped and stored under refrigerated conditions (39-46°, 4-8°C) to ensure vitality. Every order is shipped with a temperature monitoring sensor specifically calibrated for Visbiome. This card helps to ensure your order was not compromised by heat events during transit.

Visbiome can be stored at room temperature for up to one week without adversely affecting potency.

Visbiome is non-GMO, lactose-free, Gluten-free, and Kosher.

It is made in the USA.