Clinically proven UC management, without adverse side effects.

Designed to complement standard UC therapy, Visbiome helps reduce inflammation, improve gut balance, and support remission. Find the perfect product for you.

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Based on 7,435 Reviews
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Visbiome GI Care UC

Why Visbiome is Clinically Effective in the Dietary Management of UC

Decades of research support the benefits of the De Simone Formulation, as a medical food, in the dietary management of UC symptoms.

A Proven Complement to Standard UC Therapy

Living with Ulcerative Colitis is challenging—abdominal pain, diarrhea, and urgent bowel movements can disrupt your daily life. Research shows that balancing your gut microbiome plays a crucial role in managing UC symptoms and supporting long-term remission.

Visbiome® is a high-potency probiotic medical food designed to complement your UC treatment plan. By promoting a healthier gut environment, Visbiome helps reduce inflammation, support mucosal healing, and improve digestive comfort where it matters most—in your gut.

Reduces Inflammation

Helps balance the immune response, easing discomfort and promoting gut healing.⁷

Enhances Mucosal Healing

Aids in repairing and protecting the intestinal lining for improved gut function.⁶⋅⁴

Supports Remission

Clinically proven to help maintain symptom control and reduce flare-ups.¹⁻⁸

Dysbiosis in IBD

Reduced diversity of the microbiota

Decrease of SFCA-producing bacteria

Increase of mucolytic bacteria

Increase of sulfate-reducing bacteria

Increase of pathogenic bacteria

Outcome on host immunity & mucosal integrity

Decrease of energy source in epithelial cell growth and differentiation

The alteration of regulatory T cell differentiation

Degradation of mucus; increase of bacterial invasion

Enhancement of epithelial cells damage; induction of mucosal inflammation

Alteration of mucosal permeability

Dysbiosis affects the host immune system and barrier integrity, resulting in chronic inflammation

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No Serious Adverse Effects

As a medical food, Visbiome has been the subject of 7 controlled clinical trials on UC with more than 500 patients. No serious adverse effects were reported.

Visbiome was shown to be well tolerated with minimal adverse effects alone or in combination with 5-ASA and/or immunosuppresants.

Mild side effects include abdominal bloating, gas, and flatulence generally associated with changes to the gut flora.

Our Money Back Guarantee

If you’re not satisfied, we’re not satisfied. We stand behind our products, that’s why we offer a money-back guarantee for Visbiome products. Money Back guarantee is available for purchases through Visbiome.com, call center, and retail pharmacies nationwide.

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Money Back Guarantee

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250,000+ people use Visbiome.

4.8

Based on 7435 reviews
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  • Julie Miller

    Gastroenterologist recommended.

    We are having great success managing my 15-year-old daughters UC since adding Visbiome to her daily regimen. Definitely worth the money!

  • Sonali Rosete

    Very effective for UC

    My doctor recommended Visbiome in addition to a strict whole food plant based diet for managing my ulcerative colitis. This combination has been more effective than immunosuppressants, which I’ve been able to stop taking.

  • Lynda Simons

    Seems to be working!

    My Gastroenterologist recommended Visbiome as something to help my UC, which had been flaring up. It seems to be helping with this, and I am slowly getting better. I will be ordering this regularly to keep me healthy!

  • Laura Johnston

    Best Probiotic for UC!

    I have had UC for 16 years and this is by far the best product I have ever taken for it. I started taking it during my last flare up when nothing else would provide any relief, and noticed a difference within only a couple of days! I am so grateful for Visbiome and cannot recommend it enough!
Read all Reviews

Passionate experts striving for your relief.

The team at Visbiome work toward one common goal: your wellness and symptom relief. Visbiome was founded in 2015 by Marc Tewey and Yamil Hernández, two pharmaceutical industry veterans with a passion for probiotics. From the beginning, their goal was to continue Professor Claudio De Simone’s legacy of innovation in probiotics and develop a portfolio of new probiotics and live biotherapeutics (probiotic drugs) for both people and pets.

Handled with the best care.

Guaranteed.

Visbiome products are stored and shipped refrigerated to maintain the potency of live bacterial strains. Each shipment includes a temperature sensor which tracks the temperature during transit and ensures it remains within the optimal range for potency.

Backed by science. Trusted by experts.

With over two decades of research and 100+ clinical studies, Visbiome delivers clinically tested solutions for gut health. Our high-potency probiotic uses carefully selected bacterial strains to help restore balance and support digestion. Built on a foundation of science and backed by experts, Visbiome is trusted by healthcare professionals and patients alike for real, life-changing relief.

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The Visbiome Blog

Insider Insights From Gut Experts

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References

1: Bibiloni et al. Am J Gastroenterol. 2005;100:1539-1546.

2: Tursi A, et al. Med Sci Monit. 2004

3: Huynh Hien Q, et al. Inflamm Bowel Dis 15: 760-768 (2009)

4: Sood A., et al. Clin Gastroenterol Hepatol 11:1202-9 (2009)

5: Tursi A. et al. Am J Gastroenterol. 105:2218-27 (2010)

6: Lee J., Moon G., et al. Korean J Gastroenterol Vol. 60 n. 2 94-101 (2012)

7: Ng SC, et al. Inflamm Bowel Dis. 2010;16:1286–1298.

8: Miele E, et al.  Am J Gastroenterol. 2009;104:437–443.